PTPN22, CTLA4, FcγRIIa, FcγRIIIa and FcγRIIIb polymorphisms in Tunisian patients with systemic lupus erythematosus
نویسندگان
چکیده
منابع مشابه
Pregnancy Outcomes in Patients with Systemic Lupus Erythematosus
Background & aim: Pregnant women with systemic lupus erythematosus (SLE) are considered to be at high risk regarding fetal complications and adverse outcomes. The aim of this study was to evaluate the fetal outcomes in pregnant women with the SLE. Methods: This retrospective study was conducted on a total of 125 patients with the SLE referred to the Clinic and Department of Rheumatology of Imam...
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متن کاملSurvival rate of patients with systemic Lupus Erythematosus
Background: Due to infections, cardio-vascular involvement and renal insufficiency, patients with systemic lupus erythematosus live shorter than usual. Objective: To determine the mean survival rate of SLE patients. Patients and Methods: 62 SLE patients admitted in the hospitals of Kerman University of Medical Sciences from 1369 to 1380 were included in this study. The demographic variabl...
متن کاملPTPN22 and TYK2 genes polymorphisms contribute to neuropsychiatric systemic lupus erythematosus (NPSLE) in Chinese Han
Background: Neuropsychiatric manifestations pose diagnostic and therapeutic challenges in systemic lupus erythematosus (SLE). The aim of this study was to investigate whether the PTPN22, IRF5 and TYK2 polymorphisms are involved in the development of NPSLE. Material and methods: The association was investigated between three immune-associated genes (PTPN22, IRF5 and TYK2) polymorphisms and SLE p...
متن کاملT Lymphocyte Apoptosis in Systemic Lupus Erythematosus Patients
Objective(s): Apoptosis is a tightly regulated process and plays a crucial role in autoimmune diseases. Because abnormalities in apoptosis are considered to be involved in the pathogenesis of systemic lupus erythematosus (SLE), in present study we studied the apoptosis in T lymphocytes from Iranian SLE patientsat protein and gene expression levels for some molecules which are involved in apopt...
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ژورنال
عنوان ژورنال: International Journal of Clinical Rheumatology
سال: 2019
ISSN: 1758-4272
DOI: 10.4172/1758-4272.1000216